I had things running at 2133 for a time as well, but after adding a second 7970 it had a lot of stability issues.
I think the problem is not with the UP4, but the Sandy Bridge E's memory controller, its simply not as fast as the performance counterpart, but it's quad channel so it more than makes up for it. Perhaps when the Ivy Bridge E's ship, we will be able to unlock our 2400Mhz DDR3s.