I've been watching this thread for a while now and thought I would post my experience.
I built a Core i7 930 system a couple of months back using a GA-X58A-UD3R rev 1 board and 6GB of Corsair DDR3-1600 ram (XMP profile 1 enabled in bios). The system build went ok but I immediately noticed the high pitched noise described in this thread, it was coming from the CPU area and not the Seasonic X-750 power supply. The noise was very much reduced with C1E disabled.
I was willing to live with the quiet high pitched noise but I began to suffer from random crashing, particularly in games such as COD4. No blue screen of death, just instant reboot. A full hardware and software rebuild later and the same issue occurs, I eventually isolate the power supply as the most likely cause.
To cut a long story short, I bought a Corsair TX 650w power supply to prove my theory (rather than return all the bits to Scan) and I now have perfect stability with only slight coil whine when C1E is enabled (perfectly silent when disabled). I may have had a faulty Seasonic X-750 (now refunded) but this particular PSU has come up a couple of times in this thread, either way I'm much happier now.