Actually I am having a problem, that's why I considered doing it.
Machine after leaving it off overnight, the first few startups will result in either a freeze or a spontaneous reboot. Tried RMAing the board with the store and still doing the same thing. Only thing that can cure it is to run one DIMM only. I'm suspecting it's the CPU since there has been reports about similar issues with two DIMMs, but thought I'd try the BIOS.