I am having this issue where after a while with any keyboard, the D key is not registered while holding down the control key. The D key does work however if I hold the D key and then press the control key. As you know this is a crucial key combination for gaming. The only way to fix this issue is to restart my computer. While in windows if I go through the trouble shooting option, it tells me that there may be some incompatibility with USB 2.0 devices and USB 3.0 ports. From what I've read there shouldn't be any issue especially with any newer keyboard. Is there a known issue with this motherboard as far as USB 2.0 devices and USB 3.0 compatibility? I really have no idea how I can figure out what is causing this issue. BTW this motherboard has no USB 2.0 ports so I have no way of testing if the issue still occurs if plugged in via USB 2.0.