Hi there,
Have you tried removing your sound card? There have been a few instances where this has been the cause of such problems especially when running alongside NVidia graphic cards (a driver clash I think?) and it might be worthwhile eliminating this before looking at other components.
I would say that your 650 Watt PSU is more than adequate, especially with your system specs. However, the graphic cards you are trying to use are all higher spec and it might be worthwhile, if possible, trying a lower spec GPU just to see if the problem is with the Mobo PCIE slots or the initial power draw being asked for by the graphic cards.