Not so far. Only real problem I've had was a code 18.... The source of the problem was found 18 inches in front of the monitor.
If you use a raid setup and flash the bios, the defaults are reinstated, that is no raid. I you try to boot ,the process breaks the logical raid array. And you're fackered. I fixed it by booting off the Ultimate BootCD and running the raid repair process. Then resetting the BIOS to raid5 and away we went.