I just set the:
Ratio to 42
XMP Profile1
Turbo Boost Disabled
Memory Performance Enhance Standard
Load-Line Disabled
All DRAM voltages to Normal
Everything else on Auto or its default
I got 4.5 but required more drastic settings than what it is worth to me. My suggestion is to see what it can do normally first, then see what you can get out of it and store those profiles.