Greetings Exelite: and welcome.
I had a similar problem with my EP43-UD3L board about 6 months after I bought it.
I removed the board from the case and replaced the thermal paste on both the north and south bridge heatsinks, and my video card, I used Noctua NT-H1 paste, but any quality paste should work. Since I have done that, my temps have dropped across the board and remained stable.
You should also check the all voltages in the bios to make sure that they are within spec.
If the North bridge voltage (MCH) is too low for the amount of ram installed that can cause random lockups and non responsiveness (don't ask how I know
), after I installed ram in all 4 slots I had to bump my Northbridge voltage up by .1v at a time to make the system stable, end result was a .2v increase in Northbridge voltage to make stable. Most NB voltages are set to play nice with only 2 slots of ram in use. Also, check your timings and voltages for the ram itself, as that can cause similar symptoms. If you still have issues with the board, after this, come on back and we will see if we can help you resolve this,
Hope this helps.