Can't see why not, also you do realize it has 2 6x8 pwr connectors & not the standard 6x6? So hope you have a PSU that can handle this.
Also are you using air or water cooling in your case as there may be some space issues if you use water.
From what I have seen this is one cool card.
Let me know how it works out, plus how about an insight into what type of system you are running?
Ben.
PS. Sorry about the delay been having some fun?? showing the missus how to use my laptop. I wont let her near my desktop.