I don't think that it will make any difference anyway but I would set it to disabled as that is the default setting.
Enable is default for SATA Port0-3 Native model.
No I'm afraid that you're mistaken there Peter the manual says:
SATA Port0-3 Native Mode (Intel ICH10R South Bridge)Specifies the operating mode of the integrated SATA controllers.
Disabled Allows the SATA controllers to operate in Legacy IDE mode.
In Legacy mode the SATA controllers use dedicated IRQs that cannot be shared with other device. Set this option to Disabled if you wish to install operating systems that do not support Native mode. (
Default)
However I stand by my original statement that it will probably make no difference.