Hi there,
There really shouldn't be any difficulties in running your RAM in Dual Channel Mode. Unganged is the better option for a Quad core CPU, but you should also be able to run in Ganged mode if you wish too.
Just to help you understand a bit about your RAM. Although you have got 2X2GB the actual memory available is going to be a bit more. For example I have 8GB of RAM but in BIOS or if I run Memtest, it always shows that I have 8,387,584Kb (just over 8 Gig). This is due to the way the Kb's on the modules are calculated and it's easier to say 4 Gigabytes rather than, for example, 4,125,357 Kilobytes.
You don't say which version of BIOS you are currently using but F7 updates the AGESA code. This is the code that affects the CPU and the way it "talks" to the other parts on the Mobo and which might actually address the problem. So, I would think it would be a good step to update BIOS first, just to eliminate that as a problem. Once you have done that, don't forget to load Optimized Defaults and then see what happens.
If you are still having problems after you update BIOS, post back. In the meantime I will do a bit more digging for you.