I meant to type BIOS F6, not F5. After reading some suggestions from Microsoft regarding similar issues with internal card readers, I uninstalled all of the USB Host Controllers in Device Manager and restarted the PC. Let windows find the USB devices, determine it didn't have the right drivers, had Windows find the right ones, and then installed them. That whole process didn't fix my issue.
But now I have a different issue, and don't know if it's related. I can't get into BIOS now. After repeatedly hitting the DEL key on startup, either after a complete shut down, or a restart, it just skips past BIOS and loads Windows. I have a Logitech wireless keyboad and mouse that both use USB transmitters. They seem to work fine, but hitting the DEL key during POST just doesn't open BIOS up. I ran into this issue last week, but got around it by using my backup wired keyboard (still USB though).