I have been having the same problem with this software however I would like to add something about the strange nature of the issue.
I am also running on Win 10 with Dual monitors. I have however noticed that if I change my screen "layout" as in changing the second monitor to be my primary, or changing the alignment so that monitor 2 is now on the right of monitor 1 instead of the left. The software appears. Unfortunately for my case, I don't want to do either of these things as the monitors are slightly different and I want them this way around on purpose.
While unlikely, hopefully this will help in determining the problem?
EDIT:
I am running windows 10 PRO 64Bit with a Z170X - Gaming 5