No, absolutely no difference.
Gigabyte Support also asked me twice to uninstall and what version of Windows I have, but nothing makes a difference.
So next thing to do:
What windows 10 build are you running?
Use macrium reflect, Acronis, cloze zilla or windows back up and create a full disk image of your OS.
Now reinstall windows. If you have another version of the build you are running now, even better.
Install the Recon3Di software and test.
eSupport is likely testing the software now, it might speed things up if you doing some of your own testing.
Regardless of the results, you can revert to your existing install. Note, if you have any data disks attached, I'd disconnect them during reinstall and testing.