Happened again, so I went for a bios update. I also made sure to turn off the floppy controller in the BIOS (entirely turned it off). I suppose that could have been causing the ruckus the whole time as I don't recall what the setting was prior to the bios flash, but so far it hasn't happened since. My next try is the IR port (if needed), which I should probably disable anyhow since I don't use it, but I've seen other people having similar issues where that didn't help.
I guess I'll wait and see if it happens again and go from there. I appreciate all of the back and forth though. If nothing else it got me thinking...