Hi absic,
Thanks for your reply - when I tried the 'bare minimum' setup that I mentioned it was all outside the case, with literally just the CPU with heatsink/fan and the power button plugged in (I even tried a different power switch on another case to rule it out!)
The motherboard has built in video and sound, so I can't remove these, and the memory is 2 x 4GB Kingston ValueRAM (DIMM 240-pin, DDR3), but even without this installed it doesn't get any further.
Just in case it's still relevant (although none of these are attached when trying to get it working), I'm using a Fractal Design Define R3 Case, and 8 x 2TB Samsung HD204UI Spinpoint F4 hard drives (using the machine as a file server).
I followed the instructions in the manual to clear the CMOS, and have removed and re-installed the CPU, but still no luck!